The biggest upset of the 2012 Wimbledon tennis tournament didn't come until the last possible moment of day 4. Shortly after 10 p.m. London time, with the Centre Court roof closed to ward off the darkness outside, the two-time champion and three-time runner-up fell to 26-year-old Lukas Rosol of the Czech Republic, 6-7 (9-11), 6-4, 6-4, 2-6, 6-4.

It is the earliest that Nadal has departed the All England Lawn Tennis and Croquet Club as a loser since 2005, when he was also bounced in the second round by Gilles Muller.

Rosol simply overpowered Nadal, hitting 22 aces to the Spaniard's 19 and recording 65 winners to Nadal's 41. Prior to defeating Nadal, Rosol had never advanced past the first round in Southwest London.

Elsewhere around the grounds, the form largely held. On the women's side, Maria Sharapova and Serena Williams advanced to the third round, while Scottish fan favorite Andy Murray defeated the difficult Ivo Karlovic in four rounds. In addition, the top-seeded American, Mardy Fish, defeated Britain's James Ward in five sets, while Andy Roddick swept aside Germany's Bjorn Phau 6-3, 7-6 (7-1), (6-3).

A complete 2012 Wimbledon scoreboard with live updates is available here.

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